I started doing Weight Watchers a couple months ago...so far I've lost 12 pounds (maybe more...I go to weigh in tonight)
It's a good program...it's basically just watching what you eat, and making sure you get enough water, milk, fruits, vegetables etc. You can buy their food, but you definitely don't have to. It's geared to be something you can live with for the rest of your life, not just something to lose weight and then go back to your bad habits. You can look for meetings in your area by going to www.weighwatchers.com
I gained a lot of weight in nursing school since I didn't have time to work out like I did in high school, combined with eating like crap! I've just started working out again.
I'm finishing up my day orientation in the ER and going to night shift this Monday. I know they eat all night long, and I've heard all their horror stories about how they gained X lbs when they went to nights, and I vow that it won't happen to me! Probably what I'll do with working out is working out the morning after I get off if I'm not back in that night, and working out on my days off. I have more time though, b/c I'm not married and I don't have children. You could look into getting some exercise tapes, a treadmill or something at home. And you can walk anywhere, like outdoors or the mall. A lot of exercises can be done on the living room floor...crunches, push ups, squats etc.
Hope some of this helps!